Folie 1

Safety of spine SBRT: myelopathy

Multi-institutional analysis:

• 9 cases with radiation induced myelopathy

• 66 cases w/o radiation induced myelopathy

Sahgal IJROBP 2012

1 fraction

3 fractions

5 fractions

1%probability

9.2

14.8

18.2

2%probability

10.7

17.4

21.5

3%probability

11.5

18.8

23.1

4%probability

19.6

24.4

5%probability

12.4

20.3

25.3

• Doses converted to 2Gy equivalent dose (EQD2/2)

• Dmax to thecal sack

• LARGE confidence intervals

SBRT for verterbal metastases - Matthias Guckenberger - 2014