Folie 1

SBRT for re-irradiation

Re-irradiation tolerance and recovery

Factors associated with recovery:

• Initial biological dose in relationship to tolerance dose

• Initial volume irradiated

• Time interval between treatment courses

Skin & mucosa

Small intestine

Mesechymal

Bone

Full – partial

Partial

Lung

pneumonitis Lung fibrosis

Heart

Bladder

Kidney

Full – partial