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SBRT for re-irradiation
17
26 minipigs, uniform 30Gy in 10 Fx
Reirradiation after 1 year:
• Inhomogeneous (10-90%) SRS
• 14.9Gy – 25.4Gy
ED
50
of 19.7Gy
Identical SRS tolerance as in the
primary situation
Full recovery of 30Gy in 10 Fx within
1 year
Medin IJROBP 2011
Spinal cord tolerance – reirradiation:
Animal studies