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SBRT for re-irradiation

18

Spinal cord tolerance:

re-irradiation with hypofractionation ( SBRT)

Sahgal IJROBP 2010:

Case-control study:

• 5 cases of RM after SBRT

• Thecal sack as OAR

• Maximum dose to thecal sack

• 2Gy equivalent with α/β=2Gy

Clinical Practice:

0% risk of myelopathy if

Initial course <50Gy (EQD2/2)

SBRT course <25Gy (EQD2/2)

Interval >5 months