551 / 1311
Isolated regional failure after IMRT
Yao
et al.
IJROBP
2005;6:101-8.
Shoenfeld
et al.
IJROBP
2008;71;377-85.
Duprez
et al.
IJROBP
2011; 79:450-8.
Yossi
et al.
Cancer Radiother
2015; 19:73-81.
Study
n
Median
follow-up
(year)
Chemo,
n
(%)
Elective neck
D (Gy)
Isolated regional
relapse
Yao 2005
150
1.5
68 (45)
50-60
2%
Schoenfeld 2008 100
2.7
54 (54)
50-54
2% at 3 years
Duprez 2011
285
2.3
92 (32)
56-66
3% at 2 years
Yossi 2015
167
2.9
130 (77)
50
4.2%
<5%
What are results of elective neck irradiation?
Isolated regional failure –
lymph node relapse in cN0/pN+ after elective neck
irradiation.
De-intensification of
elective neck irradiation
Swallowing
disturbances
≥50 Gy