598 / 1311
Uncommon toxicity: new OARs or the RVR?
Rosenthal
et al.
IJROBP
2008;72:747-55.
Murthy
et al.
Head Neck
2014;
Gulliford
et al.
Radiat Oncol
2012;104:205-12.
Toxicity
Toxicity
rates
IMRT
+
chemo
Structure
Dose
Occipital scalp epilation
40%
25%
Occipital scalp
D
max
> 30 Gy
Anterior oral mucositis
9%
22%
Anterior
mandible
D
max
> 34 Gy
Nausea
76%
98%
Brainstem
D
mean
> 36 Gy
Emesis
38%
68%
Hypothyroidism
65%
82%
Thyroid gland
~D
min
Acute fatigue G≥2
(PARSPORT)
74%
-
Posterior fossa
Cerebellum
Brainstem
~D
mean
~D
max
What are OARs?