602 / 1311
PTV
PTV
GTV
CTV
GTV
CTV
Castadot
et al.
Radiother Oncol
2010;95:209-17.
Troost
et al.
J Nucl Med
2010;51:866-74.
Hentschel
et al.
Int J Radiat Biol
2009;85:796-804.
Per-treatment GTV (PET) volume changes
(observational studies)
Reference
Radiotherapy
technique
Per-treatment
imaging/autosegmentation
method
Δ per-treatment
volume/
pretreatment volume
Castadot 2010
IMRT
FDG-PET/
gradient-based
GTV-T
Week 2,3,4,5: -3.9%/day
Troost 2010
IMRT
FLT-PET/
signal-to-background ratio
GTV-T
Week 2: -4%
Week 4: +19%
Hentschel 2009
3D-CRT
FDG-PET/
signal-to-background ratio
GTV
sum
Week 1/2: +33%
Week 3/4: +51%
Week 5/6: +92%
Per-treatment target volume changes