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PTV

GTV

CTV

Adaptive radiation therapy

“Adaptive radiotherapy is a close-loop radiation treatment

process where the treatment plan can be modified using

a systematic feedback of measurements.”

(Yan et al, 1997)

Measurements:

• Tumor & OAR anatomy (position, shape & volume):

• Intra-fraction

• Inter-fraction.

• Tumor & OAR biology (multiparameter biologic image-defined).

• Treatment dose.

Yan

et al.

Phys Med Biol

1997;42:123-32.

Do we need adaptive radiotherapy?