

PTV
GTV
CTV
Adaptive IMRT
Chen
at al.
Head Neck
2014;83:986-93.
Schwartz
et al.
IJROBP
2012;83:986-93.
Madani
et al.
Radiother Oncol
2011;80:1045-55.
Trigged
Planned
End-point/measurement
Anatomic
n
= 51
Dose
n
=22
Biologic
n
= 21
Tumor site: oropharynx
Other
22 (43%)
29 (57%)
22 (100%)
-
11 (52%)
10 (48%)
Median follow-up (month)
30
31
25
2-year local control
-
100%
95%
2-year regional control
-
95%
93%
2-year locoregional control
78%
-
-
Topography of locoregional
recurrence
4 high-dose PTV
Not
reported
2 GTV (PET)
1 Elective neck
Do we need adaptive radiotherapy?