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Optic nerve tolerance & risk
Stupp trial (Ataman EJC 2004)
The recommended maximum doses were below 55 Gy
for the optic chiasm (and brainstem)
In QA on 53 cases; optic chiasm dose known in 48
Max dose > 55 Gy in 10/48 cases (i.e. ~ 20%)
Ataman Eur J Cancer 2004: 40: 1724-1730