Challenges
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Highly distensible, V depends on filling
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Moving (positioning, respiration, bowell filling)
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SimDVH unlikely the same as TxDVH...
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Aim at constant bladder filling (difficult to maintain)
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Different regions – Different endpoints
Hellebust TP, Radiother Oncol 2001
Muren LP, Radiother Oncol 2003
Turner SL, IJROBP 1997
Viswanathan AN, et al. IJROBP 2010
Full and empty bladder
scans (for ITV generation)
Bladder