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GUSTAVE ROUSSY
THÈME DU DIAPORAMA
RTOG-0724
Lead Group:
RTOG
SWOG
NSABP
NCIC
NCCTG
GOG
ECOG
CALGB
ACOSOG
POST-OP HIGH RISK CERVICAL
CANCERS:
Phase III Randomized Study of
Concurrent Chemotherapy and Pelvic RT
With or Without Adjuvant (Pacli + Carbo
every 21 days x 4 cycles) Chemotherapy in
High-Risk Patients with Early-Stage Cervical
Carcinoma Following Radical Hysterectomy
To Date:
163
Target:
400
(09/15/14)
GOG-0263
Lead Group:
GOG
SWOG
RTOG
NSABP
NCIC
NCCTG
ECOG
CALGB
ACOSOG
POST-OP INTERMEDIATE RISK
CERVICAL CANCERS:
Randomized Phase
III Clinical Trial of Adjuvant Radiation Versus
Chemo-radiation in Intermediate Risk, Stage
I/IIA Cervical Cancer Treated with Initial
Radical Hysterectomy and Pelvic LND
dissection
Target:
534
Ongoing studies
Depth of stromal invasion and LVSI to be pathologically
confirmed:
• Positive capillary-lymphovascular space involvement
and
one of the following:
• Deep third penetration
• Middle third penetration, clinical tumor ≥ 2 cm
• Superficial third penetration, clinical tumor ≥ 5 cm
• Middle or deep third penetration, clinical tumor ≥ 4 cm