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GUSTAVE ROUSSY

THÈME DU DIAPORAMA

RTOG-0724

Lead Group:

RTOG

SWOG

NSABP

NCIC

NCCTG

GOG

ECOG

CALGB

ACOSOG

POST-OP HIGH RISK CERVICAL

CANCERS:

Phase III Randomized Study of

Concurrent Chemotherapy and Pelvic RT

With or Without Adjuvant (Pacli + Carbo

every 21 days x 4 cycles) Chemotherapy in

High-Risk Patients with Early-Stage Cervical

Carcinoma Following Radical Hysterectomy

To Date:

163

Target:

400

(09/15/14)

GOG-0263

Lead Group:

GOG

SWOG

RTOG

NSABP

NCIC

NCCTG

ECOG

CALGB

ACOSOG

POST-OP INTERMEDIATE RISK CERVICAL

CANCERS:

Randomized Phase III Clinical

Trial of Adjuvant Radiation Versus Chemo-

radiation in Intermediate Risk, Stage I/IIA

Cervical Cancer Treated with Initial Radical

Hysterectomy and Pelvic LND dissection

Target:

534

Ongoing studies

Patients with clinical stage IA2, IB or IIA squamous,

adenosquamous, or adenocarcinoma of the cervix who have

any/all of the following high-risk f atures after surgery:

• Positive pelvic nodes

• Positive parametrium

• Positive para-aortic nodes- completely resected, PET/CT

negative (PET only required if positive para-aortic nodes

during surgery)