Porth's Essentials of Pathophysiology, 4e - page 13

xv
Introduction to Pathophysiology xviii
UNIT 1 • Cell and Tissue
Function 1
CHAPTER 1Cell Structure and Function 1
Functional Components of the Cell 1
Cell Metabolism and Energy Storage 8
Integration of Cell Function 12
Tissues 17
CHAPTER 2Cellular Responses to Stress, Injury,
and Aging 31
Cellular Responses to Persistent Stress 31
Cell Injury, Death, and Senescence 36
CHAPTER 3Inflammation, the Inflammatory
Response, and Fever 49
General Features of Inflammation 49
Acute Inflammation 53
Chronic Inflammation 61
Systemic Manifestations of Inflammation 62
CHAPTER 4Cell Proliferation and Tissue
Regeneration and Repair 71
Cell Proliferation and Tissue Regeneration 71
Healing by Connective Tissue Repair 78
CHAPTER 5Genetic Control of Cell Function and
Inheritance 87
Genetic Control of Cell Function 87
Chromosomes 95
Patterns of Inheritance 98
Gene Technology 99
CHAPTER 6Genetic and Congenital
Disorders 106
Disorders Involving Single or Multiple Genes 106
Chromosomal Disorders 115
Disorders Due to Environmental Influences 120
Prenatal Screening and Diagnosis 124
CHAPTER 7Neoplasia 129
Characteristics of Benign and Malignant
Neoplasms 129
Etiology of Cancer 137
Clinical Manifestations 144
Screening, Diagnosis, and Treatment 147
Childhood Cancers and Late Effects on Cancer
Survivors 153
UNIT 2 • Integrative Body
Functions 159
CHAPTER 8Disorders of Fluid, Electrolyte, and
Acid–Base Balance 159
Composition and Compartmental Distribution of
Body Fluids 159
Water and Sodium Balance 167
Potassium Balance 177
Calcium, Phosphorus, and Magnesium Balance 181
Acid–Base Balance 191
CHAPTER 9Stress and Adaptation 206
Stress and Adaptation 206
Disorders of the Stress Response 215
CHAPTER 10Disorders of Nutritional Status 223
Energetics and Nutritional Status 223
Overweight and Obesity 230
Undernutrition and Eating Disorders 234
UNIT 3 • Hematopoietic Function 241
CHAPTER 11Disorders of White Blood Cells and
Lymphoid Tissues 241
Hematopoietic and Lymphoid Tissues 241
Nonneoplastic Disorders of White Blood Cells 246
Neoplastic Disorders of Hematopoietic and
Lymphoid Origin 249
CHAPTER 12Disorders of Hemostasis 261
Hemostasis and Blood Coagulation 261
Hypercoagulability States 267
Bleeding Disorders 269
CHAPTER 13Disorders of Red Blood Cells 277
The Red Blood Cell 277
Anemia 282
Polycythemia 291
Age-Related Changes in Red Blood Cells 291
UNIT 4 • Infection and Immunity 297
CHAPTER 14Mechanisms of Infectious Disease 297
General Concepts of Infectious Diseases 297
Epidemiology of Infectious Diseases 306
Diagnosis of Infectious Diseases 311
Treatment of Infectious Diseases 314
New and Emerging Infectious Diseases 316
CHAPTER 15Innate and Adaptive Immunity 318
Introduction to the Immune System 318
Innate Immunity 325
Adaptive Immunity 331
Developmental Aspects of the Immune System 341
CHAPTER 16Disorders of the Immune
Response 344
Hypersensitivity Disorders 344
Transplantation Immunopathology 352
Autoimmune Disease 354
Immunodeficiency Disorders 358
UNIT 5 • Circulatory Function 375
CHAPTER 17Control of Cardiovascular
Function 375
Organization of the Circulatory System 375
Principles of Blood Flow 378
The Heart as a Pump 382
C o n t e n t s