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Contents
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Blood Vessel Structure and Function 402
Disorders of the Arterial Circulation 404
Disorders of Arterial Blood Pressure 420
Disorders of the Venous Circulation 436
Coronary Artery Disease 444
Endocardial and Valvular Disorders 457
Disorders of the Pericardium 465
Cardiomyopathies 468
Heart Disease in Infants and Children 472
Heart Failure 486
Circulatory Failure (Shock) 500
UNIT 6 • Respiratory Function 513
Structural Organization of the Respiratory
System 513
Exchange of Gases Between the Atmosphere and the
Lungs 520
Exchange of Gases Within the Lungs 528
Oxygen and Carbon Dioxide Transport 530
Control of Breathing 535
Respiratory Tract Infections 539
Cancer of the Lung 552
Respiratory Disorders in Children 555
Physiologic Effects of Ventilation and Diffusion
Disorders 565
Disorders of Lung Inflation 568
Obstructive Airway Disorders 572
Interstitial Lung Diseases 586
Disorders of the Pulmonary Circulation 588
Acute Respiratory Disorders 592
UNIT 7 • Kidney and Urinary Tract
Function 599
Functional Anatomy of the Kidney 599
Elimination and Endocrine Functions of the
Kidney 611
Tests of Renal Function 614
Disorders of Glomerular Function 621
Tubular and Interstitial Disorders 628
Obstructive Disorders 631
Malignant Tumors of the Kidney 636
Acute Kidney Injury 639
Chronic Kidney Disease 643
Chronic Kidney Disease in Children and Elderly
Persons 652
Control of Urine Elimination 656
Disorders of Lower Urinary Tract Structures and
Function 661
Urinary Tract Infections 667
Cancer of the Bladder 671
UNIT 8 • Gastrointestinal and
Hepatobiliary Function 675
Organization and Function of the Gastrointestinal
Tract 675
Gastrointestinal Innervation and Motility 680
Secretory Functions of the Gastrointestinal
Tract 686
Digestion and Absorption in the Gastrointestinal
Disorders of the Esophagus 696
Disorders of the Stomach 701
Disorders of the Small and Large Intestines 705
The Liver and Hepatobiliary System 724
Disorders of Hepatic and Biliary Function 731
Disorders of the Hepatobiliary System and Exocrine
Pancreas 745
UNIT 9 • Endocrine System 753
The Endocrine System 753
General Aspects of Altered Endocrine
Function 767
Anterior Pituitary and Growth Hormone
Disorders 768
Thyroid Hormone Disorders 775
Adrenal Cortical Hormone Disorders 783
Hormonal Control of Nutrient Metabolism and
Storage 793
Diabetes Mellitus 799