95 / 172
Methods (Published)
•
GC – MS
•
SFC Method SFC‐DAD
•
UHPLC MS DAD ‐ ‐
•
Triple Quadrupole MS
•
Linear Ion Trap MS
•
LC‐MS with quadrupole mass spec (scan mode)
Methods (FDA)
FDA Method
–
FDA has not used a screening method
–
NPA submitted FOIA for FDA’s quantitative method
•
GC‐MS method single quadrapole – full scan spectra
•
Mitragynine Q Ion 214, Confirmation Ions 397, 383, 186
800000
900000
1000000
1100000
1200000
1300000
Scan 1705 (14.642 min): 07071404.D
397
214
Spectra and
Q/Confirmation Ions of
20 ug/mL mitragynine
solvent standard
50 100 150 200 250 300 350 400 450 500 550 600
0
100000
200000
300000
400000
500000
600000
700000
m/z-->
269
186
367
75
158
342
129
240 311
103
429 503 477 553 614641
579