Slide 1

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Inter-fraction motion
of primary GTV
GTV
CTV
PTV
• 5 consecutive MRI’s during EBRT
• Impact of changes in bladder and bowel filling on
position changes of uterus
• Not only one organ is responsible
Low impact
Low impact
High impact of
bladder and bowel
High impact of
bladder
Target motion & Bladder filing effect during EBRT
Van de Bunt et al 2008
Courtesy : Ina Schulz, Utrecht