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TUMOR REGRESSION DURING EXTERNAL RADIATION THERAPY

Significant changes in tumor volumes occur during EBRT

Tumors shrink & often quite quickly with CTRT

Shrinkage is a double-edged sword

University of Utah used physical exam measurements and found by 30.8 Gy tumors reduced by 50%

MD Anderson used weekly conventional CT & noted a mean reduction of 64%

Lee et al. Red Journal 2005;58:625

Beadle et al. ASTRO 2006

Mayr et al. Am J Roentgenol 2006;187:65

Van de Bunt et al. Red Journal 2006;64:189