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9/13/2016

3

Background on the Analyte (continued)

Cranberries containing proanthocyanidins are typically not consumed “as is” due

to their naturally low sugar content and high acid content, compared to common

fruits such as apples and grapes, and instead are used in a wide variety or ways

or products such as beverages, sauces and relishes, dried cranberries, snacks,

ingredients (juice concentrate, dried powders, extracts) and dietary supplements

In addition to urinary tract health, proanthocyanidins contribute to the antioxidant

activity exhibited by cranberry and other fruits rich in polyphenolic compounds

Significance (or implications)

Companies want to market products (foods, dietary supplements, medical foods

and botanical drugs) that can be formulated to deliver effective and consistent

concentrations of proanthocyanidins to consumers

Need to standardize products used by researchers for clinical studies

Companies need to evaluate the impact of processing on and the shelf-life of

proanthocyanidins in various products