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How to Control the Primary Tumor

in Metastatic Disease

Prospective randomised study (AUS, NZL, CAN & UK)

R

A

Palliative RT: 35 Gy, 15 fr (Can und UK) or

30 Gy, 10 fr (AUS, NZL)

N=220

(151 AC)

Penniment MG et al.

ASCO-GI

2015; abstract 06

N

D

O

M

Same RT;

concomitant Cisplatin and 5FU (d1-4)

Advanced

(mostly

metastatic)

disease

Primary endpoint: improvement of dysphagia (>1 pt on Mellow scale)