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How to Control the Primary Tumor

in Metastatic Disease

Toxicity

Chemo-RT n (%)

RT n (%)

Oesophagitis

102/111 (92%)

94/109 (87%)

Skin toxicity

75/111 (67%)

62/109 (56%)

Combined radiochemotherapy is more toxic

Penniment MG et al.

ASCO-GI

2015; abstract 06

Mucositis

32/111 (29%)

11/109 (10%)

Intestinal side effects

54/111 (48%)

22/109 (20%)

Fever

22/111 (19%)

12/109 (11%)

Nausea & emesis

103/111 (92%)

85/109 (78%)

Other side effects

79/111 (71%)

61/109 (56%)