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How to Control the Primary Tumor

in Metastatic Disease

.4

.6

.8

1

Cumulative incidence of dysphagia response

Dysphagea relief

Chemo-

RT

versus RT

(p=0.34)

1.00

Survival

Improvement ~70%

Penniment MG et al.

ASCO-GI

2015; abstract 06

0

.2

0

1

2

3

4

5

6

Time (months)

Chemo-radiation

Radiation only

0.00 0.20 0.40 0.60 0.80

Survival

109

57

29

15

10

8

6

Radiation only

111

65

27

12

11

8

7

Chemo-radiation

Number at risk

0

6

12

18

24

30

36

Time (months)

Chemo-radiation

Radiation only

Group

(p=0.89)

Radiatio without chemo

sufficient for control

of dysphagia

after 3 months