825 / 1084
Epidemiology of gastric cancer
• Europe ~140,000 cases/year; ~107,000 deaths
• The Netherlands >2,000 cases/yr; ~1,000 deaths
• 3
rd
cause of death from cancer worldwide
• Distal cancers decreasing; tumors of cardia or GEJ increasing
• Proximal gastric cancer associated with reflux disease
• Distal gastric cancer associated with
H. pylori
• 65% T3-T4; 85% N+; 30% liver metastases
Buas et al. Semin Radiat Oncol 2013