827 / 1084
High locoregional failure rates after curative resection
Recurrences
Mean
Range
Locoregional - only
54%
(29-72%)
Locoregional - total
88%
(38-94%)
Distant - only
25%
(18-35%)
Gunderson et al. 1982; Smalley et al. IJROBP 2002; Lim et al. Br J Cancer 2004