85 / 1084
• CROSS - 2015 (Trimodality)
T1N1+T2-3N0-1M0
Junction= 24%
366 pts
Adeno 75%
Signif SVV Benefit
Preoperative
Chemoradiation
Planned Esophagectomy
Van Hagen
et al
; N Engl J Med 2012
Oppedijk
et al;
JCO 2014
Shapiro
et al
; Lancet Oncol 2015
RTCT: 41.4 Gy (1.8 Gy fx) + Carbo/Paclitaxel
EQD2: 40.71 Gy
The Netherlands