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Preoperative
Chemoradiation
Planned Esophagectomy
• Burmeister et al – 2005
Preoperative
Chemoradiation
Planned Esophagectomy
Mid-Distal 79% 256 pts Adeno 62%
EQD2: 36.17 Gy
Tumor site
N. Histology
EQD2
• CROSS - 2015
Mod from Cellini
et al
; Radiat Oncol 2014
(Italy)
Junction 24% 366 pts Adeno 75%
EQD2: 40.71 Gy
Statistically in favour of Preop ChemoRT
Stage: T1N1+T2-3N0-1M0
Stage: T1–3, N0–1 M0