93 / 1084
Preoperative
Chemoradiation
Planned Esophagectomy
•
Walsh et al – 1996 (Trimodality)
Phase III Trial Chir
±
Preop RTCT
•
CROSS - 2015 (Trimodality)
Phase III Trial Chir
±
Preop RTCT
•
POET - 2009 (Trimodality)
Phase III Trial Chir + Preop CT
±
RT
•
Urba et al – 2001 (Trimodality)
Phase III Trial Chir
±
Preop RTCT
•
Burmeister et al – 2005 (Trimodality)
Phase III Trial Chir
±
Preop RTCT
•
Tepper et al – 2008 (Trimodality)
Phase III Trial Chir
±
Preop RTCT
State of art of radiation therapy in Esophageal Cancer
•
FFCD 9901 - 2014 (Trimodality)
Phase III Trial Chir
±
Preop RTCT
Definitive
Chemoradiation
Salvage Esophagectomy
• RTOG 85-01 - 1999
Phase III Trial RT vs RTCT
• INT 0123 - 2002
Phase III Trial RTCT (50Gy) vs RTCT (65Gy)