92 / 1084
•
Propensity score match
Preoperative
Chemoradiation
Planned Esophagectomy
442 ptz available
multi-center (10 Europe)
resectable Esophageal or GEJ Siewert type I and II
(stage II or III), adenocarcinoma 100%
•
ypT0
=
NCR+S=
26
.7% versus NC+S=
5%;
p
<0.001
;
•
R1/2 resection margins
=
NCR+S= 7.7% versus NC+S= 21.8
%;
p
< 0.001
;
Evaluation period 2001-2012; follow-up until 2015
Markar SR et al – Ann Oncol - 2016
(Ireland)
•
ypN
0
=
NCR+S=
63
.3% versus NC+S=
32.1%;
p
< 0.001
;
•
lymph node harvest
=
NCR+S= 14% versus NC+S= 27
%;
p
< 0.001
;
•
30+90-day mortality
=
No sign diffs
•
anastomotic leak
=
NCR+S= 2
3.
1% versus NC+S= 6.8
%;
p
< 0.001
;