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PDE5-003

Is the method safe to use as written?

Yes

Are there any safety concerns with

any component, instrument, reagent

or instruction of the method? If yes,

please clearly state the concerns.

None that are not addressed

Does the method include all

necessary safety precautions and/or

warning statements? Yes or No. If

No, please suggest potential

precautions or warnings that can be

added to the method for users or

recommend safer option(s) if

warranted.

yes

Recommendations

Final Recommendation:

I think the weaknesses can be addressed and that this

could be a very valuable screening method for PDE5

inhibitors and related inhibitors.