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Background
Existing Methods
•
SciFinder search: “turmeric and validation” and “2014‐2015”
yielded 97 references
•
Spectrophotometric method for the estimation of curcumin
in bulk and pharmaceutical formulation
•
1H‐NMR and PCR for detecting
Curcuma longa
wild species
adulterants
•
HPLC and LC/MS are widely used
analytical techniques
Workgroup meetings
Method Performance Requirements
–
High and low analytical range
–
Reproducibility (RSDR)
•
Original: ≤2%
•
Group discussion: ≤10%
•
After input from the industry members of the group:
≤3 and ≤6%
–
Repeatability (RSDr)
•
Original: ≤1%
•
Group discussion: ≤5%
•
After input from the industry members of the group:
≤2 and ≤4%