1482 / 1983
Results of BCT with radiotherapy in
BRCA
carriers.
Retrospective study comparing
BRCA
mutation carriers vs. non carriers
Period of
study
Selection
criteria
Median f/u
(yrs.)
No.
BRCA
1/2
No.
Non-
mutated
Carriers
Non-
carriers
p
Haffty
Lancet 2002
1975-
1998
Age < 42
Pts. Alive
only
12.7
22
(15/7)
105
41
29
0.007
% 10-year IPBR