175 / 1983
Polish Colorectal Study Group
Bujko K. Br J Surg. 2006;93(10):1215-23
•
312 patients.
•
Randomisation
–
SCRT 25/5 + early surgery
–
LCRT 50.4/28 + 5-FU/FA + delayed surgery
SCRT LCRT
p value
Crude LR
9% 14.2% 0.170
4-year OS
67.2% 66.2% 0.96
Acute toxicity
3.2
18.2 < 0.001
Late toxicity
10.1% 7.1% 0.360