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Parameters for clinical outcome: Small bowel
Kavanagh BD et al. Radiation Dose-Volume effects in the stomach and small bowel.
Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S101–S107, 2010.
0
50
100
150
200
250
300
350
400
450
500
0
5
10
15
20
25
30
35
40
45
Dose (Gy)
Absolute Volume of
individual bowel loops
[cc]
High risk (≈40%) of G3
or worse acute toxicity
Low risk (≈10%)of G3 or
worse acute toxicity
Baglan-Robertson threshold model for risk of acute small bowel toxicity
CTCAE G3
: Abdominal pain, fever,
change in bowel habits with ileus;
peritoneal signs
Cord length [mm]
ED
50
paralysis (Gy)