1095 / 1416
Complex clustered damage
(3 or more components)
ssb + base damage
base lesions
dsb + base lesions
particle,
(high- LET)
:
70 - 90 %
dsb are complex
(additional breaks and/or base damages)
•
more clustered DNA
damagema
Particle effects on DNA damage and repair
Incidence of DNA damage after photon and proton radiation
Irridiated plasmid DNA
Leloup et al. 2005