1133 / 1416
Modified from M. Goitein, AAPM Symposium 2009
Pagane< 2014
d
o
s
e
depth
physical
dose
biol. effec1ve
dose
center SOBP
RBE
~
1.05
entrance region
RBE
~
1.0
RBE raises across SOBP
distal edge
RBE
~
1.25
elongaAon of range
? 1 – 2 mm
……. are
very similar
to photons,
due to the increase in RBE,
refinement
might be necessary !
generic RBE = 1.1
all posiAons, all dose levels per fracAon, all Assues
Normal Assue
Radiobiological properties of high energy protons
Normal Assue
distal
dose fall-off
RBE
~
1.5