1132 / 1416
Protons
RBE determination along the
proton depth-dose profile
5 +10 cm SOBP, 87 / 200 MeV modul. beam
V79 hamster fibroblasts
V79 cell line
Bri$en et al. 2012
Belli et al. 1998
Calugaru et al. 2011
RBE
changes
considerably
along the depth-dose distribu?on,
most previous studies determined
the RBE in the mid-SOBP
Proton RBE correlated with LET !
Database to be extended with:
in-vivo RBEs for normal :ssue
late effects
(proximal, mid and distal SOBP)