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High-LET irradia-on and TICS
Identification of tumor-
initiating cells (TICS)
in untreated tumors
FACS sorting of
CD24+/CD45-
cells in
the tumor sublines AT1, HI and H
tumor induction rate of
TICS from untreated
tumors
(in vivo limited dilution assay)
R3327-HI, wildtyp
R3327-HI, sorted
Glowa et al. unpublished