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Surrogate for Organ Motion : Online – Offline

matching (Intrafraction)

Mean X

Lateral (mm)

Mean Y

ANT-POST

(mm)

Mean Z

SUP-INF (mm)

Day 5

5.3

7.9

6.4

Day 10

4.9

7.8

7.6

Day 15

4.7

8.8

7.2

Day 20

6.4

7.5

8.7

Day 25

4.7

7

9.6

Parameter

Error (in mm) measured along

X-Axis

(RT – LT )

Y-axis

(ANT-POST)

Z-axis

(SUP-INF)

SD of Random

error (σ)

4.3

5.8

6.6

SD of systematic

error (ξ)

2.2

2.6

3.4

TMH Study; ASTRO 2014

Daily CBCT IGRT

Nodal CTV matching

Mid RT Tumor Regression with MRI

Tumor regression: the mean cervical tumor

volume reduced from 58.4 cc at diagnosis to

28.3 cc) at mid treatment

Cervical cancer with intact Uterus

N = 40 patients with FIGO IIB-IIIB