602 / 1119
Stratified Randomization
Type of Hysterectomy
Use of Concurrent Chemotherapy
Post Hysterectomy
Needs Adjuvant RT
N=120
Standard RT
N=120
IG-IMRT
(Tomotherapy)
CTCAE version 3.0, QOL (EORTC QLQ C30 & Cx-24 )
Interim Analysis Planned : 50% complete F/up of 18 mths.
Phase III RCT of Postoperative Adjuvant Conventional Radiation (3DCRT) Vs. Image Guided
Intensity Modulated Radiotherapy (IG-IMRT) for Reducing Late Bowel Toxicity in Cervical
Cancer (PARCER): Interim Analysis (Tata Memorial Centre)
Hypothesis: IMRT will significantly reduce grade ≥ II late bowel toxicity with postoperative radiation