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Primary Endpoint

Median Follow Up = 20 months

14% absolute difference; statistically insignificant at interim analysis

IG-IMRT

3DCRT

p value

Late Grade ≥ II toxicity

(Primary Endpoint)

11.4%

25%

0.13

Late Grade ≥ III toxicity

(Exploratory Endpoint)

3.2%

17.8%

0.02

S Chopra et al; ASTRO 2015