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12 overlapping symptoms

CTCAE & EORTC QLQ

nr.of

“quite a bit” or “very

much” problems reported

nr.of

discrepancies

(CTCAE G0)

diarrhea

27

13

anal incontinence

17

15

bleeding hemorrhage GI

1

1

urinary frequency

52

23

urinary incontinence

15

7

bleeding hemorrhage GU

2

1

limb edema

21

10

fatigue

53

22

insomnia

53

26

hot flashes

73

19

vaginal dryness*

22

11

vaginal stenosis*

24

11

*comparison in sex. active pat. only

N=223 patients

at 3 months FUP

In total 360 substantial

problems reported

159 (44%) of

substantial problems

not recognized by

physician assessed

CTCAE