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Agreement physician assessed vs.

Patient reported symptoms

Kirchheiner et al. SUON 2012

N=223 cervical cancer, CTCAE v3 vs. EORTC C30 + CX24

3 months after end of definitive radiochemotherapy

>1 time/hour, urgency,

catheter indicated

Increase >2 times of

normal, but < hourly

Increase in frequency

or nocturnia up to 2

times of normal,

enuresis

None

very much

quite a bit

a little

not at all

G0 G1 G2 G3 CTCAE Urinary frequency

EORTC : Did you pass water / urine frequently?

Discrepancy

:

Patient reported symptom

“quite a bit” to ”very much”

in EORTC QLQ

→ CTCAE grading 0

not at

all

a little

quite

a bit

very

much