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Copyright 2013 American Medical Association. All rights reserved.

Although there was no significant difference in the objec-

tive findings among the different age groups, the subjective

severity of LPR in geriatric patients is significantly greater

than in younger patients. Furthermore, older patients are

more likely not to respond to PPI therapy than younger

patients.

ARTICLE INFORMATION

Submitted for Publication:

July 2, 2013; final

revision received August 18, 2013; accepted

September 7, 2013.

Published Online:

November 7, 2013.

doi:10.1001/jamaoto.2013.5556.

Author Contributions:

Dr Eun had full access to all

of the data in the study and takes responsibility for

the integrity of the data and the accuracy of the

data analysis.

Study concept and design:

Y. C. Lee, Kim, Kwon, Eun.

Acquisition of data:

Y. C. Lee, J. S. Lee, Kim, Kwon,

Eun.

Analysis and interpretation of data:

Y. C. Lee, J. S.

Lee, Eun.

Drafting of the manuscript:

Y. C. Lee, J. S. Lee.

Critical revision of the manuscript for important

intellectual content:

Kim, Kwon, Eun.

Statistical analysis:

Y. C. Lee, J. S. Lee

.

Study supervision:

Kim, Kwon, Eun.

Conflict of Interest Disclosures:

None reported.

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Age and Proton Pump Inhibitor Treatment

Original Investigation

Research

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JAMAOtolaryngology–Head &Neck Surgery

December 2013

Volume

139, Number

12

89