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Diffusion Response Markers
Diffusion MRI used in
>60 therapy studies
Therapy effects:
Decrease in high b-
value signal intensity
Increase in tumour ADC
≥30%
Early response (14d)
assessment achievable
Afaq A et al. Cancer Imaging 2010; 10: S179-188;
Bains LJ et al. Cancer Imaging 2012; 12:395-402
ADC: 0.74 to 1.05 x10
-3
mm
2
/s