Index
991
Pilocarpine, 488–490, 958
Pimecrolimus, 263, 264
Pindolol, 477, 478, 676
Pineal gland, 514
Pinocytosis, 72, 75
Pinworm infections, 180
pinworms, 179
Pioglitazone, 587, 588, 589
Piperacillin, 109
Piroxicam, 247
Pituitary agents.
See
Hypothalamic and
pituitary agents
Pituitary gland, 513, 515, 516
anterior pituitary, 512, 515, 516
intermediate lobe, 515, 516
posterior pituitary, 512, 515, 516
Placebo effect, 16, 27, 46
Placenta and breast milk, 23
hormones and, 514
Plague, 282
Plants, 3–4, 5
Plasma, 774, 775
Plasma esterase, 416, 426
Plasminogen, 750, 754
Plasmodium
, 163, 164–166
Platelet aggregation, 750, 751, 752
Platyhelminths (flatworms), 179, 181
Pneumococcal vaccine, 274, 279
Pneumocystis carinii
pneumonia, 163, 172
Pneumonia, 834, 838
Pneumothorax, 834, 838
Podophyllotoxin, 952
Podophyllum resin, 952
Poisoning, 31, 36
Poisons
uniform scheduling, 9, 10
Poliomyelitis vaccine, 280
Polycystic ovary syndrome
hypoglycaemic drugs, 589
Polydipsia, 572, 575–576
Polyphagia, 573, 575
Poractant, 881
Posaconazole, 151–154
Positive inotropic effect, 681, 683
Posterior pituitary, 512, 515, 516
hormones, drugs affecting, 521,
530–533
adverse effects, 533
care considerations, 533
contraindications and cautions,
532–533
drug–drug interactions, 533
pharmacokinetics, 532
therapeutic actions and indications,
530
Post-marketing surveillance, 2, 8
Postmenopausal osteoporosis, 551, 563,
564
Postoperative nausea and vomiting,
933–934
Potassium channel openers, 714, 716,
825–726
Potassium regulation, 798
potassium-rich foods, 814
Potassium-sparing diuretics, 658, 803,
806, 813–814
Povidone-iodine, 950
Pralidoxime, 491, 492
Pramipexole, 374–376
Prasugrel, 756, 758
Pravastatin, 738, 740–741
Praziquantel, 183, 185, 186
Prazosin, 471, 475, 483, 676
Preclinical trials, 2, 6
Prednisolone, 539, 542, 543
Prednisone, 356, 539, 542–544, 545–547
Pregabalin, 354, 365–368
Pregnancy, 8–9, 600–601
adrenergic agonists, 456
adrenergic blocking agents, 471
anaemias, drugs used to treat, 779
anthelmintic agents, 183
antianginal agents, 717
antiarrhythmic agents, 701
antibiotics, 93
anticholinergic agents, 502
antidepressant agents, 318
antiemetic agents, 931
antifungal agents, 151
anti-infective agents, 82
anti-inflammatory agents, 241
antimigraine agents, 410
antineoplastic agents, 194
antiparkinsonism agents, 375
antiprotozoal agents, 164
antiseizure agents, 354
antiviral agents, 128
anxiolytic and hypnotic agents, 304
blood pressure, drugs affecting, 667
cardiotonic agents, 686
cholinergic agonists, 489
classification of drugs, 9
coagulation, drugs affecting, 752
corticosteroids, 540
diuretic agents, 807
female reproductive system, drugs
affecting, 608
gastrointestinal secretions, drugs
affecting, 899
hypoglycaemic agents, 574
hypothalamic and pituitary agents, 523
immune modulators, 260
laxatives and antidiarrhoeal agents, 917
lipid-lowering agents, 736
lower respiratory tract agents, 866
male reproductive system, drugs
affecting, 629
muscle relaxants, 386
neuromuscular junction (NMJ)
blocking agents, 435
opioids, 401
psychotherapeutic agents, 335
thyroid and parathyroid agents, 554
upper respiratory tract agents, 844
urinary tract agents, 820
Premature atrial contractions (PACs),
696, 699
Premature ventricular contractions
(PVCs), 696, 699, 700
Pre-medication, 416, 418
Prilocaine, 425, 426
Primaquine, 166–168
Primidone, 357, 358–359, 362
Prinzmetal angina, 713, 715
Proarrhythmic, 696, 701
Procaine penicillin, 108, 109
Procarbazine, 195, 197
Prochlorperazine, 200, 335, 336, 337,
929, 931, 932, 934
Progesterone, 596, 597–600, 607, 609,
612–614, 619
effects, 599
Progestogens, 606, 607–608, 610,
613–614
adverse effects, 613
contraindications and cautions, 613
drug–drug interactions, 613
pharmacokinetics, 610
Promethazine, 313, 853, 854, 931, 932
Propafenone, 702, 703
Propamidine isethionate, 958
Propantheline, 502, 503
Prophylaxis, 81, 86
Propionic acids, 240, 246, 247
Propofol, 354, 417, 420, 421
Propranolol, 469, 471, 477–479, 676,
696, 698, 701, 703–705, 716, 722
Propylthiouracil, 552, 554, 557, 560, 561
Prostaglandins, 606, 620, 622–624, 896,
901, 910–912
adverse effects, 622, 911
care considerations, 623–624, 911–912
contraindications and cautions, 622,
910–911
pharmacokinetics, 622, 910
therapeutic actions and indications,
622, 910
Prostate gland, 800
Protamine sulfate, 757, 766
Protease inhibitors, 126, 136, 139–140
adverse effects, 140
contraindications and cautions,
139–140
drug–drug interactions, 140
pharmacokinetics, 139
therapeutic actions and indications, 139
Proteasome inhibitors, 220–222
adverse effects, 221
contraindications and cautions, 221
drug–drug interactions, 222
pharmacokinetics, 221
therapeutic actions and indications,
220–221
Protein binding, 22
Proton pump inhibitors, 896, 900,
906–908
adverse effects, 898, 907
care considerations, 907–908
contraindications and cautions, 907
drug–drug interactions, 907
interstitial nephritis, 908
pharmacokinetics, 907
therapeutic actions and indications,
906–907
Protozoa, 163, 164
Protozoal infections, 164, 170–172
agents for, 172–174
adverse effects, 173
