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21

TUESDAY, SEPTEMBER 26, 2017

8:15 AM – 9:45 AM

New Blood 2017: Developing Methods for the Detection of

Chemical Residues, Contaminants and Important Analytes

The detection of chemical analytes, residues, and contaminants

in consumer commodities and the environment is an interesting,

challenging, and continually evolving discipline. In order to maintain a

vibrant and active Chemical Contaminants community in AOAC, young

scientists must be encouraged to work in these areas. The purpose of

this session is to provide new members of our community an opportunity

to present their work for the first time at a technical session at the

AOAC Annual Meeting. The presentations in this session represent

the broad interests of the AOAC Chemical Contaminants Community

that emphasize the analysis of pesticide and veterinary drug residues,

environmental and industrial contaminants, adulterants, natural toxins,

and other important chemicals or issues in food, feed, environmental

samples and other relevant matrices. It is hopeful to continue the

tradition to have a New Blood session at every AOAC meeting dedicated

to new and talented AOAC scientists, stakeholders, and members.

CO-CHAIR:

Alexander Krynitsky,

Symbiotic Research, LLC

CO-CHAIR:

Michael McLaughlin,

U.S. Food and Drug Administration,

Office of Regulatory Affairs

CO-CHAIR:

Jon Wong,

U.S. Food and Drug Administration,

Center for Food Safety and Applied Nutrition

Arne Duebecke,

Quality Services International GmbH

NMR Profiling of Honey: Combining Targeted and Non-Targeted

Analysis in Routine Analysis

Yu-Ching Hung,

Taiwan Food and Drug Administration

A Novel Target to Identify Edible Animal Fats Adulterated

with Cooked Oil

James Wang,

Symbiotic Research LLC

Ways to Overcome Matrix Effects When Developing Methods

for LC-MS/MS

Challenges in Food Allergen Management: Effective Tools

and Practical Considerations

Food allergen management is a difficult task for the food industry

and all other stakeholders involved. Regulations are very diverse with

few regulated thresholds, making it challenging to interpret results

“correctly”. Test kit manufacturers aim to develop analytical methods

that meet the demands of the food industry. As this industry has diverse

needs, a one-for-all solution is not achievable. On the other hand,

academic research is focusing on food allergen mass spectrometry

methods which are typically not suitable for the inevitable in-process

testing in food production environments.

This session will link these different aspects of food allergen

management and explain the challenges each party faces. An overview

about the history of allergen legislation sheds light on the different

regulations that apply and why it is so difficult to find common and

detailed rules. The lack of allergen threshold levels is not only a

challenge for the food industry, but also for test kit manufacturers who

need to ensure that their testing solutions are compatible with the

indefinite range of applications. Close cooperation between the food

producer and the test kit supplier is crucial to achieve the required high

level of food safety. Specific demands and real-life experiences from

the food industry’s perspective will also be part of the discussion, as

well as the latest results of the iFAAM ring trial that give an overview of

the current capabilities of analytical methods. The discussion will also

cover the advantages and disadvantages of immunological and mass

spectrometry based methods and give an outlook of considerations for

future approaches.

CO-CHAIR:

Carmen Diaz-Amigo,

FOCOS GbR

CO-CHAIR:

Gavin O’Connor,

European Commission – Joint

Research Centre

Bert Pöpping,

FOCOS GbR

The History (and Future) of Allergen Labeling Regulations: These

Could be Simple, but we Insist on Making them Complicated

Kurt Brunner,

ROMER Labs Division Holding GmbH

Immunological Methods for Allergen Detection: Challenges and

How to Deal with them

Clare Mills,

University of Manchester

Analysis of Allergens in Foods in a Risk Assessment Context:

The role of Immunoassay and MS Methods

Prabhakar Kasturi,

PepsiCo Inc.

Practical Considerations about Food Allergen Testing from

an Industry Perspective

Characterization of Botanical Extracts Using

Multiple Technologies

Most commercially available Botanical Reference Materials (BRMs)

used for identity testing are botanicals in their original form (leaf,

root, seed, etc.). This can present problems when BRMs are used to

verify the identity of botanical extracts, which may or may not have a

similar profile to the unprocessed botanical. For proper identification of

botanical extracts, Botanical Extract Reference Standards are needed.

Whereas powdered botanicals typically retain most of the chemical

constituents found in the original plant material due to light processing

(e.g., grinding), botanical extracts undergo complex and vigorous

processing (such as solvent extraction, fractionation, distillation,

fermentation, addition of excipients, etc.) which can cause significant

changes in the chemical profile. Scientists tasked with verifying the

identity of botanical extracts must understand how processing steps

can affect the composition of an extract reference material, as well

as understand which reference materials are appropriate for use for

each sample.

This session is intended to cover the important considerations for

characterization of botanical extracts by assessing their unique

profiles. Various technologies are available for characterization of

the chemical components in botanical extracts, including HPTLC and

HPLC checking the chromatographic profile with separation, and NMR

analyzing the spectroscopic profile, LC-MS combining the physical

separation capabilities of liquid chromatography with the mass analysis

capabilities of mass spectrometry.

All these considerations need to be addressing during full

characterization of botanical extracts with different technologies. This

session proposes to cover this topic by scientists with expertise in

different techniques.