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24

WWW.AOAC.ORG

301.924.7077

WEDNESDAY, SEPTEMBER 27, 2017

8:15 AM – 9:45 AM

Committee on Statistics Symposium: Ideas for Target

Measurement Uncertainty, Intermediate Precision, and

Collaborative Studies — Review and Meta-Analysis

Members of the AOAC Committee on Statistics will present statistics

supporting target measurement uncertainty and the Analytical Target

Profile as described in recent USP articles as it relates to the upcoming

revision of the ISO 17025. Furthermore, there will be a presentation on

intermediate precision, its generalization and how to design a study for

its measurement. Additionally, a review of quantitative collaborative

studies for a chemical analyte published in

J. AOAC

from 2000 to

2016 were identified and the reported statistical results tabulated. A

meta-analysis of the results was performed and an evaluation made

of possible performance requirements based on tolerance limits of the

observed population of studies and compared to the HORRAT system will

also be presented.

CHAIR:

Sidney Sudberg,

Alchemist Labs

Jane Weitzel,

Consultant

Statistics to Support Target Measurement Uncertainty and the

Analytical Target Profile as Described in Recent USP Articles

Paul Wehling,

Medallion Labs/General Mills

Intermediate Precision: Its Generalization and How to Design a Study

for its Measurement

Sidney Sudberg,

Alchemist Labs

A Systematic Review and Meta-Analysis of Quantitative Chemical

Collaborative Studies Published in

J. AOAC

from 2000 to 2016 Based

on the Logarithmic metamer pC

Applications of Metagenomics for Food Safety

Genomic technologies are now frequently used for the characterization

of foodborne pathogens, and have been beneficial in the identification

of sources of foodborne outbreaks. While such investigations typically

rely on the genomic characterization of bacterial isolates, metagenomic

analysis of more complex communities is proving to be a valuable tool

supporting food production and food safety objectives. Applications

of metagenomics include: (1) study of complex enrichment culture

growth dynamics to gain a better understanding of factors influencing

growth of pathogens in food enrichment broths leading to improved

microbiological methods, (2) characterization of bacterial communities

in food commodities and food production environments to identify

signals of potential problems, enabling early interventions to avoid

pathogen contamination of food commodities and (3) Detection of

pathogens in foodborne outbreak investigations that could not be

cultured using traditional means, enabling characterization of the

etiological agents associated with the outbreak. This session will

present some of the emerging uses for metagenomics in food safety and

describe bioinformatics methods for metagenome analysis enabling

participants to gain a better understanding of how metagenomics

technologies can be applied to improve food safety outcomes.

CO-CHAIR:

Catherine Carrillo,

Canadian Food Inspection Agency (CFIA)

CO-CHAIR:

Irene Iugovaz,

Health Canada

Karen Jarvis,

U.S. Food and Drug Administration

Pathogen Detection and Food Microbiome Characterization Using a

Metagenomics Approach

Konstantinos Konstantinidis,

Georgia Institute of Technology

Metagenomic Investigation of Foodborne Outbreaks

Sam Minot,

One Codex

Validating Microbial Metagenomics using Standardized, Reproducible

Methods with One Codex

Worldwide Perspectives on Contaminants Testing in Food and

Environmental Samples Using Advanced Analytical Techniques

We have gathered scientist from around the world in one session to

get a fully worldwide perspective of food and environmental testing

using newer technologies. In this session you can see how scientists

from Europe, Asia, Australia and North America utilize powerful modern

technologies on residue testing and gain insight on how this can help

you with your scientific endeavors.

CO-CHAIR:

Ping Wan,

Office of Indiana State Chemist

CO-CHAIR:

Steven Moser,

Oklahoma Department of Agriculture,

Food & Forestry

Walter Hammack,

Florida Department of Agriculture and

Consumer Services

High Resolution Mass Spectrometry Strategies for Targeted

and Non-Targeted Analysis in Food Samples

Mingchih Fang,

Taiwan Food and Drug Administration

High-Resolution Mass Spectrometry in Food Analysis:

Real Case Experiences from Taiwan FDA

Robert Trengove,

Murdoch University

Food and Environmental Contamination Analysis: Nice to

Have and Necessary Today, an Australian Perspective

Amadeo Fernandez-Alba,

University of Almeria

High Resolution Mass Spectrometry Experiences from the European

Union Reference Laboratory for Pesticide Residues in Fruits and

Vegetables

10:15 AM – 11:45 AM

What’s New in Carbohydrates? Functional Carbohydrate

Ingredients and Dietary Fiber Regulation

Carbohydrates are the most abundant group of natural products. They

serve as energy storage molecules (starch, glycogen), and structural

components (cellulose, chitin) in plants and living organisms.

Carbohydrates are present in all types of cell walls and cell membranes,

playing important roles in physiological and pathological processes,

such as fertilization, immunity, cancer, etc. They are also critical to

many other biological processes, such as DNA/RNA formation and

protein glycosylation. Furthermore, carbohydrates are unambiguously

one of the major macronutrients for human diet. The dietary guidelines

recommend 45–65% of a healthful diet comes from carbohydrates.

Carbohydrates are not only an important energy source but also, as

dietary fiber, provide other health benefits by promoting health and well-

being or reducing the risk of disease.

In the carbohydrate session, we will cover topics around dietary

fiber and emerging functional carbohydrate aspects, including their

definition, benefits and functions, and analytical methods. We will

discuss the current analytical progress on sialic acid, chondroitin and

GAGs, dietary fiber and human milk oligosaccharides.

CO-CHAIR:

Xun Yan,

AMWAY

CO-CHAIR:

Jon Devries,

Medallion Laboratories/General Mills