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Dynamics of the cell cycle in a growing population

FUCCI imaging of the cell

cycle: two interphase

regulators, Cdt1 & Geminin.

Cdt1 (

red

) only expressed

during G1 and early S

Geminin (

green

) only

expressed during S/G2.

human fibroblasts visualized

by time-lapse live-cell imaging

over period of 3 days

G1

-

early S

-

late S & G2