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ESTRO

Pelvic radiation with concurrent chemotherapy compared with

pelvic and para-aortic radiation for high-risk cervical cancer.

M. Morris et al, NEJM, 340:1137-1143, 1999.

Enhancement factor

Effect on tumor control

Effect on normal

tissue toxicity

5

4

3

2

1

2

3

4

5

Early

Late

Local

relapse