793 / 1173
1/03/2016
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Introduction
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Another R...
Radiation sensitivity
Recovery
Redistribution
Repopulation
Reoxygenation
iRradiated volume
RESTORATION (long term recovery)
3
Introduction
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Reirradiation of previously treated areas: why?
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New primary tumor
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Cancer survivors are at an increased risk of developing secondary
malignancies
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Pts still retain more risk (e.g. molecular predisposition)
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Aetiological factors can continue (e.g. Smoking)
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Therapy itself
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Within or close to initial high-dose treatment volume
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Recurrence
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Within or close to original gross tumor volume
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Nodes and metastases
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